Dental X-rays Can Detect Osteoporosis Symptoms

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Dental X-rays Can Detect Osteoporosis Symptoms

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A computer program that analyzes routine Dental X-rays could offer a simple, cheap way to detect the bone-thinning disease Osteoporosis, new research suggests.

Researchers in the Academic Center for Dentistry Amsterdam have created a unique way of identifying patients at risk of osteoporosis by using ordinary dental x-rays. Professor Paul F. van der Stelt and his team developed the largely automated approach to detecting the disease during a three-year, EU-funded collaboration with the Universities of Manchester, Athens, Leuven, and Malmo. They will present their findings today during the 85th General Session of the International Association for Dental Research.

Osteoporosis affects almost 15% of Western women in their fifties, 22% in their sixties, and 38.5% in their seventies. As many as 70% of women over 80 are at risk, and the condition carries a high risk of bone fractures, with over a third of adult women falling victim at least once in their lifetime. Wide-scale screening for the disease is not currently viable, largely due to the cost and scarcity of specialist equipment and staff.

The team has therefore developed an innovative software-based approach to detecting osteoporosis using routine dental x-rays, by automatically analyzing specific characteristics of the radiographic trabecular bone pattern. These features include, among others, the thickness, the amount of fragmentation, and the main orientation of the structure of the trabecular bone.

In four clinical centers, 671 women with an average age of 55 years were recruited. To obtain the "gold standard", the team measured bone thickness at the femur, hip, and spine, using the technique that is common for this kind of expensive examination (Bone Mass Density, BMD). In addition, one panoramic and two intra-oral radiographs were made...

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