NP Rank:
Early Marijuana Use May Lead to Aggressive Testicular Cancer
Findings of a study published in the online edition of Cancer on February 9, 2009 suggest that early marijuana use in men may contribute to the development of an aggressive form of testicular cancer in men under 40 known as nonseminoma.
Nonseminoma testicular cancer accounts for 40% of all cases worldwide and is the fastest growing most aggressive form of the disease. It is also the most common type of testicular cancer in men ages 15 to 34.
While testicular cancer accounts for only 1% of all cancers contracted by men the prevalence of the most aggressive form of the disease among young marijuana users is compelling. No link between the less aggressive seminoma testicular cancer and marijuana use was found.
"Since we know that the incidence of testicular cancer has been rising in our country and in Europe over the last 40 years and that marijuana use has also risen over the same time, it seemed logical that there might be an association between the two," said study co-author Janet Daling, an epidemiologist and member of the Fred Hutchinson Cancer Research Center's public health sciences division in Seattle. "And when I analyzed the data, we found a fairly strong relationship with this aggressive type of testicular cancer."No link was found between the drug and a less aggressive and more prevalent form of the disease, known as seminoma, which strikes 60 percent of testicular cancer patients.
The study demonstrated that men who smoked marijuana while young were at a 70% increased risk of developing nonseminoma testicular cancer. The men with the highest risk factor were those who used the drug at least once a week and started using before the age of 18.
The longitudinal study involved more than 1,000 men ages 18 to 44 who had been diagnosed with either form of testicular cancer between 1999 and 2006. The study included a control group of 1,000 healthy men. All participants answered a questionnaire about their lifestyle habits including alcohol and marijuana use.
"We know very little about the long-term health consequences of marijuana smoking," she cautioned. "So, although this is the first time this association has been studied and found -- and the finding does need to be replicated before we are really sure what's going on -- this does give some evidence that testicular cancer may be one result from the frequent use of marijuana. And that is something that young people should keep in mind."But the prospect of a causal relationship between marijuana use and testicular cancer raised a lot of unanswered questions for Gary Schwartz, an associate professor in both the department of cancer biology and the department of epidemiology and prevention at Wake Forest University in Winston-Salem, N.C.
"The consensus is that most testicular cancer is thought to originate with lesions in utero, and that the peak age for testicular cancer to actually occur begins, really, right after adolescence," he noted. "That's when hormones released during puberty appear to promote [full-blown] cancer by essentially throwing fuel on the lesion fire, following a relatively long latency. The point being that you don't suddenly wake up one morning with a tumor. So it's a little hard to understand how exposure to marijuana beginning at that point could somehow play an immediate causal role."
Crowd Power
-
jack pizzo.
United States -
chelseaadurr
United States -
Little Lea
United States -
prensa420
Brazil -
beerdough
United States -
xgutsk8x
United States











Most RecentMost Recommended Comments (4)
at 10:13 on February 10th, 2009
Source: freepages.misc.rootsweb.ancestry.com
Source: chinadaily.com.cn
at 19:29 on February 9th, 2009
AW Nuts!!
at 20:29 on February 9th, 2009
BEAUTIFUL MEDICAL CANNABIS
xgutsk8x has contributed a photo to this story.
at 16:34 on February 18th, 2009
i don“t believe!
prensa420 has contributed a photo to this story.