Enhancing the Understanding of Pre-Type 1 Diabetes in the General
Type 1 diabetes occurs in ∼90% of patients with no family history of the disease. The majority of studies seeking to identify at-risk subjects have been conducted in first-degree relatives who comprise just 10% of all cases of type 1 diabetes but may have a 20-fold increased risk for type 1 diabetes . Although the peak incidence occurs at adolescence, there are data to suggest that 5–10% of all adults diagnosed with type 2 diabetes may actually have type 1 diabetes (latent autoimmune diabetes in adults [LADA]). If type 1 diabetes is to be prevented..