Estimation of blood glucose control in diabetes mellitus

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Estimation of blood glucose control in diabetes mellitus

 The demonstration that the development of microvascular complications in patients with type 1 diabetes can be slowed by treating hyperglycemia has led to increased use of intensive insulin regimens to attain strict glycemic control (figure 1 and figure 2) [1-3]. The efficacy of these regimens requires an accurate method to estimate the degree to which this is achieved. It is helpful to first review some basic concepts before discussing the utility of measurements of hemoglobin A1C (HbA1c) and serum fructosamine to assess glycemic control.
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