Iatrogenic Stemetil Poisoning...!
The evidence speaks when victims cannot
"Truth cannot live on a diet of secrets
withering within entangled lies"
H. Michael Sweeney
Just as a forensic scientist can turn the smallest clue into a material witness, one can look to the medical record for clues that will bear witness to what went wrong and why. Neuroleptics (antipsychotics) are among the most dangerous medications ever used in medicine, and Stemetil is no exception. They are presently prescribed haphazardly by psychiatrists and general practitioners alike.
In simple words, they are brain damaging chemicals.
All drugs are poisons and all poisons are (potentially) drugs: drug side effects rangie from the annoying to the lethal. There is also a physical tolerance and withdrawal syndrome (excitement seizures) , and a panic factor (iatrogenic) which can kill you.
Objective: To make a greater body of awareness of definitive evidence available from all sources of information relating to the drug Stemetil that shows presence or absence of the characteristic drug signature (pattern of injury) , especially where injury is believed to be doctor caused.
Stemetil, also known as prochlorperazine is used for the treatment of the symptoms of psychotic disorders such as excessive anxiety, tension, confusion, delusions, and agitation. It works by affecting the chemical balance in the brain. It also can be used to treat or prevent nausea and vomiting caused by the use of certain medications (e.g., cancer treatments) or motion sickness.
Target focal point: Drug signature analysis/profiling of key drug induced toxicities in liver, kidney and heart tissue associated with phenothiazine type drugs. By using biomarkers of drug pathology and mechanisms from drug signature (pattern recognition) and multi-source library profiles I will demonstrate and show publicly that use of Stemetil for control of nausea can be an iatrogenic drug induced nightmare of unprecedented magnitude.
Biomarkers are genetic indicators that have been shown to be correlative with normal biologic processes, pathologic processes or pharmacologic responses to theraputic intervention.
Probable Valid Biomarkers are currently defined as those that have been measured in an analytical test system with well-established performance characteristics and for which there is a scientific framework or body of evidence that appears to elucidate the physiologic, toxicologic, pharmacologic or clinical significance of the test results.
Known Valid Biomarkers are currently defined as those that have been measured in an analytical test system with well-established performance characteristics and for which there is widespread agreement in the medical or scientific community about the physiologic, toxocologic, pharmacologic or clinical significance of the results.
The liver plays a major role in the biotransformation of drugs and toxins and thereby becomes a major target for drug-induced injury. But what about other vital organs?
Stemetil (prochlorperazine) is a high risk antipsychotic-antiemetic drug to be used with caution, and according to manufacturer's directives. The drug Stemetil is produced in Canada by Aventis Pharma: formed by the merger of Rhone-Poulenc Rorer and Hoechst Marion Roussel.
Stemetil is widely distributed into body tissues and fluids. It suppresses activity in the trigger zones of the vomiting center by paralyzing the gastrointestinal tract that governs the vomiting reflex. Stemetil undergoes metabolism in the gastric mucosa and on first pass through the liver where it enters the enterohepatic circulation and is excreted chiefly in the feces.
Each drug tends to have a signature, meaning a typical pattern of injury. In the case of phenothiazine type drugs, this pattern of injury closely mimics viral hepatitis, clinically, biochemically and histologically. Patients typically have a mixed cholestatic-hepatocellular picture as seen in both bilirubin and aminotransferase levels. But don't be fooled by normal liver enzyme levels. This is a typical feature of edited lab records by callous physicians to conceal evidence of iatrogenic injury. Turn the focus to mechanisms from drug-signature with emphasis on pattern recognition. Make a detailed list of all signs and symptoms for comparative analysis. If typical pattern of injury is present but the liver function findings tend to elucidate or do not support the facts you can be reasonably certain that the records have been messed with. This of course requires a high index of suspicion, but a simple test to confirm is to detail one topic at a time, the blood pressure, for example. List everything in chronological order according to time of event from all sources of the record. If one record documents a certain blood pressure at a certain time, and another record or chart documents something different for the very same time you know the record has been altered. Then go on to the heart rate, etc. Leave no stone unturned. By repeating the procedure from different sources you can turn the smallest clue into a material witness.
If the clinical presentation is consistent with a hepatitis-like picture and/or cholestatic reaction, the findings are compatible with drug signature. There are a variety of clinical syndromes which may in some situations overlap. Severe infection is no exception. Always be on the alert for common denominators.
Stemetil (prochlorperazine ) poisoning is marked by oversedation, respiratory depression and hypotension. Symptoms of overdosage include sedation, loss of consciousness or coma , hypotension, tachycardia, EEG changes, ventricylar arrhythmias, and hypothermia or temperature dysregulation which may mimic an afebrile state. Although many of these signs and symptoms may overlap with certain conditions there are other ways of tracing pattern of injury, such as by systematic reviewing of all relevant literature and comparing it with the events documented on a patient's medical record. You'll be surprised at what you can uncover.
Stemetil is highly bound to proteins in blood (91-99%) and has a duration of activity from 4 to 6 hours. One caveat is that the drug has a half life that can potentiate or even interact with concurrent medications, such as analgesics, for example.
Blood borne infection or meningocci in the blood lyse easily. It seems logical to assume that Stemetil would be contraindicated to infection for this reason.
Phenothiazines can potentiate and mask the signs and symptoms of overdosage of other drugs or underlying conditions, ie. organic brain syndrome, etc.. Thus patients can have exascerbation of their underlying or pre-existing conditions. The adverse effects of phenothiazines can affect all organ systems, and Stemetil is no exception; eyes, nose, and throat; internal organs such as liver, stomach, intestines, cardiovascular system, sexual organs, and especially the brain.
A great many patients suffer disastrous consequences, such as neuroleptic malignant syndrome, cardiovascular crisis, seizures, heatstroke, and sudden unexplained death, all of which can be attributed to medical stupidity and negligent use of phenothiazines, and their derivatives.
Phenothiazines type drugs are among the most dangerous medications ever used in medicine. Don't be fooled into believing that these drugs are actually treating a disease. They are suppressing overall brain and vital organ function, while creating diseases, and exascerbating illness, resulting in catastrophic decline of patient condition. Indications are primarily in the management of psychotic or mental disorders; also used to subdue patients - a chemical straightjacket. Reference: Psychiatric Insanity
The antiemetic action of Stemetil may actually mask the signs and symptoms of drug overdosage and may obscure the diagnosis and treatment of other conditions, ie. intestinal obstruction. How could they even think to market such a dangerous drug? An how could Health Canada even permit it?
Toxic doses of Stemetil can lead to changes in the blood-brain barrier (BBB), allowing an infectious agent to gain entry to the brain and produce lethal central nervous system (CNS = brain and spinal cord) infection. The scientific literature describe two bacterial factors specific to the meningitis pathogen that thwart the normal protective role of the blood-brain barrier, leading to serious infection. Further, sugar solution in IV creates gaps in the blood-brain barrier allowing chemicals to enter. Infected material can block the blood vessels to the brain, but Stemetil can help shuttle it directly into the brain and CNS.
Stemetil (prochlorperazine) enhances permeability of the blood-brain barrier and crosses the blood-brain barrier, breaching BBB integrity, thus allowing penetration of normally excluded agents, taking with it blood toxins and poisons in the blood-stream - which then triggers an inflamatory response. Bacteria invade the cerebrospinal fluid (CSF) by crossing the blood-brain barrier through a complex series of events, beginning with attachment of bacterial fibrils to the brain microvascular endothelial cells. Once in the CFS, bacteria multiply rapidly due to the absence of local defences where they further degrade the BBB and exascerbate tissue damage resulting in permanent brain injury.
Brain injury caused by drug induced meningitis related inflamation, edema, reduced blood flow (ischemia), or endogenous toxins can lead to neurologic sequalae, including deafness, mental retardation, motor dysfunction, and (secondary) epilepsy.
Stemetil is contraindicated to emesis in altered states of consciousness, coma, trauma, toxic syndromes, in the presence of blood dyscrasias, central respiratory failure, in the presence of circulatory collapse, in severely depressed patients, liver and renal insufficiency, intestinal obstruction, in patients with cardiovascular disorders, organic brain syndrome, or a history of hypersensitivity to phenothiazine derivatives.
Phenothiazines suppress sweating, causing central nervous system impairment which can infer temperature disregulation.
Stemetil contains a cardiotoxic metabolyte (having an injurious effect on the heart) which can lead to toxic myocarditis or drug induced cardiomyopathy, and subsequent heart failure. Current use of antipsychotic medications is associated with a more that tripled risk of Sudden Cardiac Death.
Stemetil is a high risk antipsychotic anti-emetic drug. Indications are primarily in the management of psychotic disorders. Stemetil (prochlorperazine) is the most potent in suppressing the reflex of nausea and vomiting. But that's not all it suppresses. Sudden deaths have occurred in hospitalized patients using this type of drug in which iatrogenic causes are suspect at the grass root level. In some cases, the deaths were attributed to cardiac arrest, while in others the cause appeared to be asphyxia due to failure of the cough reflex, the result of phenothiazine induced muscle paralysis.
Antipsychotic drugs may cause blood clots, researchers report extending previous findings. Prochlorperazine has been reported to cause heart attack, shock, stroke, and GI bleeding. Phenothiazine type drugs have even been reported to trigger diabetes in patients with no previous history of diabetes.. Neuroleptic agent toxicity in an already sedated patient can result in tachycardia, hyperthermia, urinary retension ileus, mydriasis (pupil dilation), hypoglycemia (becomes apparent as blood toxicity increases) toxic psychosis, and can even cause direct injury to the heart.
Drug Induced Dystonia is defined as a movement disorder characterized by sustained muscle contractions. freequently causing twisting and repetitive movements or abnormal postures that can result in distorted postures.It is a charcteristic feature with phenothiazine type reactions.
Dystonic reactions are thus acute spasms of muscle groups that can lead to a fixed upward gaze... painful dystonic reactions can be quite frightening to patients. These reactions typically occur soon after initiation of an antipsychotic drug. When that happens any negligence of the patient's throat secretions may lead to aspiration of vomitus or gastric content and a vicious cycle begins, which if not broken will lead to death.
Incontinence suggests loss of bladder control, or bladder paralysis, and is a very serious side effect of Stemetil, and possibly first sign of a drug reaction.
Compare: Rapid-Onset Dystonia Parkinsonism (RDP), a rare form of dystonia also characterized by dystonic spasms in the limbs, with prominant involvement involvement of the speach and swallowing muscles. Symptoms can be sudden, occuring over hours. Suppression of the gag reflex due to swallowing difficulty attributed to muscle paralysis can result in aspiration of vomitus or gastric content and ultimately, in asphyxia.
Tardive dyskinesia (TD) is also characterized by involuntary movements of the arms and legs. TD is potentially irreversable. Spontaneous dyskinesia has occured as abnormal involuntary movements in persons who have never been previously exposed to antipsychotic medications. Opisthotonus Iis characterized by spasms of the body where the head and heels are bent backward and the body is bowed forward. It occurs with drug reactions triggered by IV infusions with drugs such as Stemetil. Compare Idiopathic spasmodic torticollis, a focal dystonia associated with neuroleptic drug toxicity.
Stemetil changes a variety of chemicals in the brain. The adverse effects of Stemetil can affect all organ systems and may be attributed either to the drugÕs effects on the central autonomic nervous system, or to hypersensitivity reactions to the drug-reaction. Increased sedation is a serious side effect of this type of agent.
Symptoms of overdosage include central nervous system (CNS) depression which may vary from simple lethargy to coma. Symptoms of overdosage may be more severe than usual side effects, or two or more of the following may occur together: Falling levels of consciousness or coma; convulsions (seizures); fast or slow heartbeat; large fixed dilated pupils (also associated with shift of brain tissue and transtentorial herniation); palor; dry skin; weak pulse; low blood pressure; tachycardia; trouble in urinating; twitching or jerking movements; and vomiting. Other possible manifestations include paralytic ileus, hepatic dysfunction, renal dysfunction, gastrointestinal disturbances, respiratory depression (breathing difficulty), cardiac arrhythmias (heart failure), skin rashes or fixed drug eruption, dry eyes, ocular gyric crisis (eyes rolling back into their orbits); and simptoms resembling Parkinson's disease .
Caveat: Anticholinergic agents such as Gravol, an antihistamine, in combination with Stenetil can inhibit gastrointestinal motility which can exascerbate gastrointestinal problems, such as constipation or bowel obstruction . When the bowel stops working the body gets toxic. The effects of anticholinergic drugs such as Gravol may be potentiated by neuroleptic type anti-emetics, such as Stemetil. Use of neuroleptics in combination with anticholinergic agents may also increase the risk of tardive dyskinesia. The effects of opiate ANALGESICS (morphine) may also be potentiated similarly with concomitant or concurrent Stemetil use. Moderate to severe drug-drug interaction with Stemetil (prochlorperazine) and Dimenhydrinate (Gravol) with additive effects when used in combination or concurrently is reported in the literature. Search: Anticholinergic Syndrome. Compare Antichollinergic Toxidrome.
Life threatening: Uncontrolled mucscle twitching characterized by stiffness or spasms of the muscles, swirling tongue movements or swelling of the tongue, difficulty swallowing are all common features of the Neuroleptic Malignant Syndrome (NMS). Neuroleptic Malignant Syndrome is characterized by alterations in consciousness, and autonomic instability, such as tachycardia, hypertension or hypotension.
Stemetil poisoning is marked by oversedation, respiratory depression and hypotension. All phenothiazines can potentiate and mask the signs and symptoms of overdosage of other drugs or underlying conditions, ie. hypotension, etc. Thus patients can have exascerbation of their underlying disorders.
Phenothiazines that are clearly contraindicated in a wide variety of medical conditions have no effect on systemic infection, EXCEPT TO EXACERBATE PRIMARY or UNDERLYING CONDITIONS due to a whole array of clinical insults, any or all of which can trigger a procoagulation response which can ultimately lead to coma, circulatory collapse, and DEATH., which is also a major cause of unexplained sudden dealths in hospitalized patients, more so than most ostrich-like physicians care to admit.
The neuroleptics or antipsychotics are the most frequently prescribed drugs in mental hospitals, and are widely used in board-and-care homes, nursing homes, institutions for people with mental retardation, children's facilities, and prisons. They also are given to millions of patients in public clinics and to hundreds of thousands in private psychiatric offices AND NOW IN OUR HOSPITALS, PRESUMABLY FOR CONTROL OF NAUSEA. Often they are prescribed for anxiety, sleep problems, and other difficulties in a manner that runs contrary to the usual recommendations. And too often, they are administered to children with behavior problems, even children who are living at home and going to school. Rather than treating a disease, the neuroleptics create a disease. The neuroleptic drugs are chemical lobotomizing agents with no specific therapeutic effect on any symptoms or problems. Their main impact is to blunt and subdue the individual. They also physically paralyze the body, rendering the individual less able to react or to move. They produce a chemical lobotomy and a chemical straitjacket. The drugs are also the cause of brain damage that afflicts up to half or more of long-term patients. The original ones, including Thorazine and Mellaril, are called phenothiazines.
While the neuroleptics are toxic to most brain functions, disrupting nearly all of them, they have an especially well-documented impact on the dopamine neurotransmitter system. Dopamine neurotransmitters provide the major nerve pathways from the deeper brain to the frontal lobes and limbic system--the very same areas struck by surgical lobotomy. Most psychosurgery cuts the nerve connections to and from the frontal lobes and limbic system; chemical lobotomy largely interdicts the nerve connections to the same regions. Either way, coming or going, it's a lobotomy effect. Clinically, the drugs produce a lobotomy and neurologically the drugs produce a lobotomy. Starting from two main trunks deep in the brain, the dopamine nerves spread out like the branches of a tree, reaching into the emotion-regulating limbic system and frontal lobes. This dopamine tree is shut down by the neuroleptics.
Tardive dyskinesia is a movement disorder, frequently caused by neuroleptics drugs that can afflict any of the voluntary muscles, from the eyelids, tongue, larynx, and diaphragm to the neck, arms, legs, and torso. On rare occasions it can occur after a few weeks or months, but usually it strikes the individual after six months to two years of treatment. Some psychiatrists try to blame the neurological disorder on schizophrenia rather than on the drugs. It manifests as uncontrollable twitches, spasms, or writhing movements. Any of the neuroleptics can cause tardive dyskinesia.
We've all heard of the Chemical Straightjacket. To be put in a chemical straightjacket can be terrifying.
In summary, the neuroleptic drugs are chemical lobotomizing agents with no specific therapeutic effect on any symptoms or problems. Their main impact is to blunt and subdue the individual.n be terrifyingthey also physically paralyze the body, rendering the individual less able to react or to move. Thus they produce a chemical lobotomy and a chemical straitjacket
CONTRAINDICATIONS/PRECAUTIONS: All phenothiazines, including prochlorperazine can cause neuromuscular reactions, particularly dystonias.
Prochlorperazine can worsen conditions in patients with organic or traumatic brain damage. This is a relative contraindication, and the exact cause of this phenomenon is unknown. Patients with underlying temperature dysregulation can have this condition amplified by prochlorperazine. In patients with underlying tardive dyskinesia, prochlorperazine can worsen the condition in the long term. An alternative antiemetic or anProchlorperazine can cause hypotension, so patients with cardiovascular disorders could have exacerbation of their conditions if administered prochlorperazine. tipsychotic should be considered. Concomitant administration of prochlorperazine and other anticholinergics, including atropine, monoamine oxidase inhibitors, phenothiazines, antihistamines, antidepressants, meperidine, and antiparkinsonian agents, can cause additive adverse effects such as oversedation, paralytic ileus, and severe constipation.
Stemetil is widely distributed into body tissues and crosses the blood-brain barrier. The drug STEMETIL has a history of adverse reactions resulting in -induced hypoxia with irreversible brain damage due to oxygen starvation of the brain, including "sudden, unexpected and unexplained s" in hospitalized patients.
Parkinsn's List DataBase prochlorperazine / Compazine, ... describes Stemetil as a HIGH RISK antipsychotic-antiemetic with a history of adverse effects most commonly related to the "high potency" neuroleptic . Prochlorperazine (Canadian generic name for the same medication. Stemetil is hepatically metabolized (well absorbeed into the gastrointestinal tract, with high concentrations into the liver and spleen).
The concept of a systemic inflamatory response syndrome expresses the notion that the body responds in certain ways to a variety of insults and negligent use of Stemetil is the ultimate clinical insult, physically, and neurologically. All virtues of phenothiazines can potentiate and exascerbate similar or like-virtues of other medications known to cause respiratory depression. In frail patients, as respiratory rate decreases, the patient becomes increasingly sedated. Morphine is one drug that can lead to respiratory depression. Concomitant or concurrent use of Stemetil can result in exacerbation of this condition.
Caveat: Prochlorperazine intoxication or poisoning can also cause deep physiologic depression that resembles and can mimic brain death. SEARCH: Brain Damaging Neuroleptic Drugs.
The neuromuscular blocking effects of neuroleptic drugs are many and include nerve paralysis including neuronitis of spinal nerves. There is also a panic factor which can result in heart failure and kill you. Remember: The heart is a muscle, as are other vital organs.
Compare drug induced Rhabdomyolysis in which drug-toxicity involves vital organs : kidney, liver, gastrointestinal tract and CNS , with skeletal muscles usually being less readily affected. Drug induced Rhabdomyolysis is the breakdown of muscle fibers resulting in the release of muscle fiber content into the circulation. Rhabdomyolysis from any cause leads to inadequate blood-perfusion and subsequent renal failure - cardiogenic shock or cardiorespiratory arrest may occur exceptionally.
The bald truth is that neuroleptic drugs are chemical lobotomizing agents with no specific therapeutic effect on any symptoms or regimens, and Stemetil is no exception. Neuroleptics (antipsychotics) inhibit dopamine nerve transmission in the frontal lobes and in the emotion-regulating limbic system of the brain. This inhibition is no different than surgical lobotomy. It is chemical lobotomy. Their main impact is to blunt and subdue the individual.. They also physically paralyze the body, rendering the individual less able to react or to move. Thus they act as a chemical lobotomy and a chemical straightjacket . In some cases these types of drug can physically paralyze the intestines, vital organs, including the inspiratory muscles of the diaphragm (diaphragmatic paralysis) literally smothering the patient, resulting in overwhelming exertional fatigue or stress , the panic fright factor response to chemical straightjacket, followed by a seemingly slow and painful death due cardiorespiratory arrest in the presence of circulatory collapse. Compare with the "locked-in state", a condition in which a person is conscious and able to think, but is severely paralyzed due to nerve paralysis. In my opinion which is widely shared, neuroleptic drugs should be banned.
Put yourself in a patient's position of total or near total paralysis with most of your senses blunted, unable to move, speak or even open your eyes due to a severely paralyzed motor function - you try relentlessly to free yourseld until you become so overwhelmed by exhaustion, fright and panic that your heart begins to gives out.
Phenothiazine derivatives are multipotent receptor blockers that give rise to a large number of pharmacological responses. The receptor-mediated responses can be ascribed to either their effect on central neurotransmission or to their influences on neuronal terminal junctions in peripheral tissues. Centrally, phenothiazines are postsynaptic antagonist and they inhibit catecholamine re-uptake at neuronal terminals. The antagonism in the basal ganglia results in neurolepsis while antipsychotic effects arise from action in the limbic system and hormonal side effect from activity in the hyphothalmus.
Peripheral responses to these drugs are as a result of predominantly an adrenegis blockade. They are often complex in their pharmacological interpretation as neuronal reuptake, which reduces catechlomine-medicated responses is inhibited at the same time. Peripheral and central cholinergic antihistaminic and antiserotonin effects also contribute to the peripheral manifestation.
CAVEAT: Peripheral nerve disorders that cause paralysis can result. Examples of peripheral nerve disorders include Guillain Barre´ Strohl Syndrome, Chronic Inflammatory Demyelinating Polyneuropathy (CIPD), and Diabetic Neuropathies.
Stemetil Can Kill You...!
In order for drug to attenuate the effects of an agonist it should not be contraindicated. Contraindicated medications may backfire dramatically, provoking opposite effect for a number of reasons, such as potentially lethal incorrect dosages, especially with medications that are contraindicated and dangerous v. the failure adequately to monitor, v. failure to perform an appropriate medical screening, v. failure to determine the etiology of disorders. The term "backfire" means "to have the reverse of the desired or expected effect" - usually follows a course of inappropriate treatment due to misdiagnosis.
Toxicity of antipsychotic medications may be increased by co-ingestion of other agents, particularly drugs with similar metabolic pathways. Sedative effect may be apparent before antidepressant effect is noted. Adverse effects of medications include somnolence and sleep attacks. Sleep attacks are indistinguishable from drug induced somnolence and excessive sleepiness. Sleep attacks are defined as events of overwhelming sleepiness that occur without warning. Sleep attacks in patients taking dopamine agonists: is reported in PubMed. Symptoms that make up the tetrad of narcolepsy: Sleep attacks that last with increased sedative effects - drugs cause sleep attacks. Combining drugs such as prochlorperazine and opioids, may potentiate adverse effects, such as sedation and respiratory depression.
Neuroleptic malignant syndrome (NMS) is caused almost exclusively by the blocking of dopamine receptors with antipsychotic medications, including all types of neuroleptics (typical and atypical antipsychotic drugs).The higher the dosage of the antipsychotic, the more common the occurrence. Rapid and large increases in dosage can also trigger the development of NMS. NMS is a potentially fatal complication of therapy with antipsychotic medications.
Stemetil® is no longer being manufactured for sale in Canada.
There is growing concern in Ontario that far too many doctors are prescribing "contraindicated" medications with utter disregard for patient safety, and Stemetil is no exception. This is a very bad trend. Cases involving injury or death have been reported as allergic reactions. The exact number of Stemetil related injury and/or deaths is unknown because less than 10% of drug outcomes are reported. Many of the cases are undoubtedly the result of imprudence on the part of incompetent or negligent physicians. Medical stupidity may predispose. In my opinion, doctors who prescribe or order "contraindicated" drugs for their patients are guilty of criminal negligence. They should be divested of their right to practice medicine, fined heavily, and jailed. In cases where death results from failure to at least comply with the manufacturer's directives (WARNINGS), the exact same penalties that apply to "negligence causing death" should be handed down by indictment. The law applies equally to everyone, physicians are no exception.
Case in point: A hunter may be licenced to carry guns "for the pupose for which they are intended", namely hunting game. He has no right to discharge the guns "BLINDLY" with utter disregard for public safety. There's a similar case in point that could also be made for "reckless" licensed drivers who don't obey rules of the road and "ignore" WARNING signs, etc., etc., as a rule of thumb. Physicians who elect to act with "wanton and reckless disregard for human life" should be treated NO different. There's a barrel full of bad doctors out there that need to be shown the error of their ways, otherwise nothing changes.
A noble is to right wrongs and smite injustice whenever and wherever they encounter it for the good of those people which have been entrusted into their care. Turning a "blind-eye" to such negligence shows little or no concern for public safety. This is not unusual for a government backscratching drug trade bent on the path of corruption where grand corruption is rampant at the top level of government - a common feature of the McGuinty government in Ontario (typical of a constituency severely lacking in social and moral values), whose only values evolve around the almighty dollar, and protecting each other from being PROSECUTED. It seems clear that we are living in a nation of cowards and shirkers.
PSYCHIATRIC DRUGS: Cure or Quackery?
"Psychiatrists and Neuroleptic drugs are a regular
nightmare. Deleterious torturing techniques must dance in their heads".