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University Students Craft Anti-Cancer "BioBeer" With Resveratrol
A group of undergraduate and graduate students at Rice University have formulated a "BioBeer," a genetically engineered cancer-fighting beer infused with resveratrol, a chemical that has reduced cancer and heart disease in laboratory settings.
Resveratrol is a natural, plant-produced phytoalexin that is now available as a nutritional supplement in synthetic chemical form, which people take as a preventative measure against cancer and other diseases - though it's efficacy in this respect has not yet been proven.
All their work to date has gone into creating a genetically modified strain of yeast that will ferment beer and produce resveratrol at the same time. While the team does plan to brew a few test batches in coming weeks, these will contain some unappetizing chemical "markers" that will be needed for the experiments.
"There's no way anyone's drinking any of this until we get rid of that, not to mention that there's only one genetically modified strain of yeast that's ever been approved for use in beer, period," said Segall-Shapiro. "In short, it will be a long time before anybody consumes any of this."
So why would someone want to make beer with resveratrol in the first place? It's a naturally occurring compound that some studies have found to have anti-inflammatory, anticancer and cardiovascular benefits for mice and other animals. While it's still unclear if humans enjoy the same benefits, resveratrol is already sold as a health supplement, and some believe it could play a role in the "French paradox," the seemingly contradictory observation that the French suffer from relatively low rates of heart disease despite having a diet that's rich in saturated fats.
"I have seen some studies where it's been shown to activate the same proteins that are known to play a role in extending the life span of lab animals that are kept on low-calorie diets," said junior David Ouyang.
The students will enter their project into the International Genetically Engineered Machine competition (iGEM), where teams use genetic tools to do novel things. The synthetic biology research competition takes place November 8-9 in Massachussets.
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Most RecentMost Recommended Comments (3)
at 02:02 on October 19th, 2008
Terri Potratz, I like this story. It's good stuff. Students being actively involved in doing something - this case brewing - is better than just pure resaerch - its active learning - something that many high schools have developed but Universities don't build on - I wouln't want to try this brew at the moment - and i'm not sure about the genetically modified science usage - but good story - heres another student led alcohol story - Pupils give teachers alcohol lessons - I was invited to their alcohol free cocktail party - very good!
at 05:46 on October 22nd, 2008
Terri Potratz, I like this story, but it seems like wishful thinking on the part of students ... or another case (pun) of pranking. Alcohol consumption is associated with increased cancer risk.
Source: cancer.gov
at 09:26 on August 8th, 2009
hehe - thats good stuff. i've head of people having 'resveratrol cocktail parties' - sounded really odd to me, but after reading up on a potential health benefits of resveratrol supplements i can see why people are getting excited. i am still skeptical.