OUTLOOK: Celebrities Invade Toronto for Film Festival

Who: Adrian Grenier

What: The star of HBO’s testosterone-charged buddy comedy Entourage makes his directorial debut with Shot in the Dark, a documentary about his search for his estranged father.

Who: Brad Pitt

What: The new father stars in Babel, an epic study of anxiety and tragedy by 21 Grams director Alejandro González Iñárritu.

Who: Ed Harris

What: Harris plays the volatile genius composer in Agnieszka Holland’s biopic Copying Beethoven.

Who: Natalie Maines, Martie Maguire, Emily Robison — a.k.a. The Dixie Chicks

What: Barbara Kopple and Cecilia Peck’s documentary The Dixie Chicks: Shut Up and Sing! was inspired by the controversy over the Texan trio’s anti-Bush comments.

Who: Penelope Cruz

What: Cruz stars in Spanish auteur Pedro Almodovar’s no-frills domestic drama Volver.

Who: Heath Ledger

What: Ledger plays a heroin-addicted poet in the Australian indie film Candy, which marks the end of a 15-year career hiatus by Aussie director Neil Armfield (Twelfth Night, The Castanet Club).

Who: Jennifer Lopez and Marc Anthony

What: Real-life husband and wife star in El Cantante, a biopic about salsa legend Hector Lavoie.

Who: Jude Law, Mark Ruffalo and Sean Penn

What: Penn stars as a Huey P. Long-like Southern politician in Steve Zaillian’s new adaptation of the Robert Penn Warren novel All the King’s Men. Law is his long-suffering sidekick, and Ruffalo rounds out a supporting cast of stars that requires its own solar system: Kate Winslet, James Gandolfini, Patricia Clarkson and Anthony Hopkins.

Who: Emilio Estevez

What: The Mighty Ducks star writes, directs and appears in Bobby, an ensemble drama about Senator Robert Kennedy’s assassination.

Who: Peter O’Toole

What: The legendary Lawrence of Arabia star plays a dying Casanova in love with his best friend’s diamond-in-the-rough grandniece in Venus, a companion piece to 2003’s The Mother from director Roger Michell and writer Hanif Kureishi.

Who: Reese Witherspoon

What: Last year’s Oscar winner for Walk the Line produces and plays a supporting role in Penelope, a romantic fable about class and celebrity starring Christina Ricci.

Who: Russell Crowe

What: The telephone-throwing bad boy stars in Ridley Scott’s A Good Year, about a successful London financier who abandons the fast lane for an French idyll at a Provencal vineyard.

Who: Tom Hanks

What: Producer of the U.K. coming-of-age comedy Starter for Ten starring James McAvoy.

Who: Will Ferrell

What: Playing an uptight IRS auditor, Ferrell co-stars with Emma Thompson and Dustin Hoffman in Stranger Than Fiction, an Adaptation-like dramedy from Marc Forster (Monster’s Ball, Finding Neverland).

Who: Vince Vaughn

What: The motor-mouthed and rubber-lipped actor is the hub of the comedy road-trip documentary Vince Vaughn's Wild West Comedy Show.