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"These pharmacoepidemiological studies add to the extensive knowledge we have gathered through the CRESTOR clinical trials program, which continues to show that CRESTOR offers outstanding effects on lowering LDL-C with the additional benefit of raising HDL-C," said Elisabeth Bjork, CRESTOR Medical Science Director at AstraZeneca.The first study conducted in the Netherlands, compared the differences in incidences of hospitalisations for cardiovascular events -- including fatal and non-fatal ischaemic heart disease and stroke- between users of selected statins (rosuvastatin, simvastatin, atorvastatin, pravastatin). 76,147 statin-naive patients from the PHARMO Institute database, who had not experienced cardiovascular events in the preceding year were followed for up to two years, with a median duration of therapy of eleven months.
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